SIBO RESOURCES from Dr. Siebecker          

NEWSLETTER

LATEST PODCASTS

SIBO Studies

Click a button above for the latest SIBO Podcasts, Studies and Events

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15-20% Off Supplements at Fullscript (U.S.)

Fullscript carries over 20,000 professional-grade supplements and body care items. FSA and HSA accounts can be used. Feel free to share the link with friends and family! U.S. only.

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15% discount is automatically applied to everything at Fullscript (20% with Autoship at checkout).

Once logged in, see "Community Plans" or "Favorites" for lists of my favorite SIBO supplements.

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  Dr. Siebecker's Most Recent Quarterly Newsletter
January 2026

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      SIBO CLASSES + EVENTS       

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SIBO Support Membership Q&A
with Dr. Allison Siebecker

Live Q&A on January 13, 2026

 

Shivan Sarna and I have created a SIBO & IBS Support Program which includes a live Q&A each month.

Please join us for the next live Q&A.

The program also includes:

• 20% Supplement Discount 
  • on 20,000+ professional-grade supplements 
• SIBO Smart Search - get answers to your SIBO questions at any time
  • watch a Demo here
    

• 40+ SIBO Masterclasses 
  
  • including SIBO Diet, Testing, Treatment, Tough Cases and more
• SIBO Recovery Roadmap® Course ($499 value)
  • my SIBO course for patients - a complete SIBO DIY
• SIBO-friendly Recipe Exchange
  

$33/month

JANUARY 13 MEMBERSHIP Q&A  -  JOIN US HERE

 

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Practitioner Q&A with Dr. Allison Siebecker

January 15, 2026

as part of my SIBO Pro Course for providers

Join me and a small group of practitioners for a live SIBO Q&A to discuss your questions and cases.
The course is self-study with short (easy to fit into your schedule) lessons. Q&A's are ongoing! 

SIBO PRO COURSE Q&A & More Info  

 We've added a new AI Search feature to the course:

Ask your questions anytime, and our AI answers based on my lectures and course materials. 

Get answers in seconds, without watching all the classes - it's absolutely amazing! 

 

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SIBO Coaching with Dr. Siebecker

February  

Join me and host Shivan Sarna for individualized help with your SIBO!

We meet in a small-group of 8 or less, once a month x 4 months. 

Next group starts in February.

 

Small Group Coaching with Dr. Siebecker

 

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Cracking the SIBO Code Summit

FEBRUARY 4-10

JOIN SIBO SUMMIT HERE (free)

Free 7-day SIBO Summit, hosted by Angela Pifer. 

I'm speaking on tough SIBO cases, sharing what I've learned, along with the insights of 9 SIBO experts I interviewed (including Dr. Pimentel).

Other amazing speakers include Shivan Sarna, Nirala Jacobi, Jason Hawrelak, Ilana Gurevich, Dan Kalish and many more.

> Make sure to listen to Ruth Kriz on day 6, if you or someone you know, suffers from chronic UTI's!

This summit goes way beyond “just SIBO” and digs into the real root causes of stubborn gut issues, including:

• Mold exposure and mycotoxins
• Trauma and nervous system dysregulation
• Motility breakdown and methane-driven constipation
• MCAS and histamine overload
• Low stomach acid, weak bile flow, and poor detox
• Mitochondrial dysfunction and fatigue
• Parasites, yeast, and biofilm-driven infections

 

If you’ve done multiple protocols, tried every gut supplement under the sun, and still feel stuck… this is for you.

Register Here - free SIBO SUMMIT

 

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          RESEARCH UPDATES & NEWS             

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Updates from the American College of Gastroenterology Conference (ACG) in October, and more.

> From Dr. Pimentel on X:

Oct 14: “In paper just published, @barlowgillian and I cover the modern concepts of small intestinal bacterial overgrowth. This is not your grandparents #SIBO. We discuss myths and how we have advanced. Despite funding struggles, we have come a long way.” 
> Modern concepts of small intestinal bacterial overgrowth

Oct 27: "Today at #acg2025, @GIJANE_MD will be presenting data on colonic inertia. This is associated with extreme #constipation and not associated with #methane on breath test. Poster P2402.”

Oct 28: “Today @GabrielaGSLeite from @MASTprogram @CedarsSinai is presenting the second large scale clinical study observing a correlation between hydrogen sulphide on three-gas breath test and #dyspepsia and #GERD. More H2S=more symptoms! Not just diarrhea. Check out P4929”

Nov 18: “...First study of breath sample on same morning as scope with duodenal shotgun sequencing. Breath #methane and #hydrogensulfide correlate with microbes in the small intestine that produce those gases. Breath does=small intestine. And symptoms too."
> Hydrogen Sulfide and Methane on Breath Test Correlate with Human Small Intestinal Hydrogen Sulfide Producers and Methanogens

Nov 20: “The #REIMAGINE study of the #microbiome @MASTprogram has been so successful. We are excited to announce a collaboration @CedarsSinai @GuerinChildrens (Drs. Wozniak and Rabizadeh). The first study to look at the small intestinal microbiome of children called #PREIMAGINE.”

Dec 19: “As the holidays are here it is important to recognize this time of year can be very challenging for people with digestive diseases like #IBS/#SIBO. There are three cardinal rules: 

1. If someone does not eat something, please don't force them. You cannot imagine how much pain and bloating the wrong food can cause. In people with #SIBO the bacteria in their gut can ferment up to 60 times more than a normal person. This can be very painful.
2. Conversation and fun is more important than eating something that hurts you and the whole evening is ruined.
3. Food poisoning can cause IBS and SIBO and make those who have it worse. Don't leave food out for more than 2 hours to avoid spoiling and make sure food is properly cooked.

Have a great holiday!"

 

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          SIBO RESOURCES           

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Dr. Siebecker's You Tube

I post weekly videos and interviews to help people with SIBO.   

Interacting with my YouTube, actually helps my videos be shown to more people who could benefit. Such as:

• Subscribe
• Click the Notification bell 
• Comment
• Like a video
• Search for my channel by name at YouTube - Dr. Allison Siebecker or SIBO INFO

Thanks!

 

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Allimed Discount!

450mg Allicin/cap, 100 caps for $79.50

that's 56% off standard retail!

Allimed/Allimax Pro is used for Methane at 6 caps/day.

(more info about Herbal Antibiotic SIBO treatment Here)

ALLIMED 56% Off

(no code needed - trusted source)

Free Shipping (U.S. shipping only)

 

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Ongoing 15% Supplement Discount
at Fullscript

20% with SIBO Support Membership

I am happy to offer my readers 15% discount at my Fullscript dispensary, which carries 20,000+ high-quality professional supplements and more.

Discount is automatically applied at checkout to everything at Fullscript.
(FSA and HSA accounts can be used.)

 

To see my favorite SIBO supplements, see "Community Plans" or "Favorites".

 SIGN IN / SIGN UP HERE (free)

Feel free to share with friends and family. :)

See more Discounts Here

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NEW NAME

 

Zenbiome Dual has been renamed to Gut-Brain Reset.

This is one of my favorite probiotics for SIBO. It is often well-tolerated by those with probiotic sensitivity &/or histamine intolerance.

 Gut-Brain Reset - 15% Off at Fullscript

 

 

FODZYME

Now available at Fullscript

FODZYME is a digestive enzyme focusing on FODMAP digestion, specifically FOS/Fructans, GOS and Lactose.
This can help with foods like onions, garlic, cruciferous vegetables, dairy foods and more. 

FODZYME - 15% Off at Fullscript

 

• Study Results: "FODZYME specifically breaks down inulin in representative gastrointestinal conditions, resulting in decreased gas production while substantially preserving short-chain fatty acid and butyrate production in the model colon. Our results suggest dietary supplementation with FODZYME would decrease intestinal FODMAP burden and gas production."

 

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NEW ELEMENTAL DIETS

 

New Flavor Alert

Vanilla Coconut 

ElementAll - 15% off at Fullscript

 

Elemental Diet Powder

Named to TIME’s Best Inventions of 2025!

mBIOTA Elemental

Use code SIBO50 for $50 off, or SIBO for $25 off (one time use)

Published mBIOTA success rates for SIBO: 100% Hydrogen SIBO; 75% Methane + Hydrogen, 58% Methane SIBO/IMO.

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 Elemental Diet Ordering

Some elemental diets are available only through a practitioner.

However, patients can order the following Elemental Diets themselves, via:

1. Functional Medicine Formulations 

 

● Elemental Heal Whey Free (elemental diet)
● Elemental Heal (semi-elemental) - add oil separately   
● Elemental Heal Low Carb (semi-elemental) - add oil separately   
● MCT Oil powder - to add to semi-elemental diets above

Use code ALLISON15 for 15% off

(discount code applies to all supplements they carry)

 

2. My Fullscript Dispensary (15% off)

● Integrative Therapeutics: Physicians Elemental Diet and Physicians Elemental Diet Dextrose-Free
● Bioclinic Naturals: ElementAll
● Vita Aid: Elemental Nutrition and Keto-Elemental Nutrition

No Code needed - discount is automatically applied to everything at Fullscript

 

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SIBO Books

Clinical Understanding of the Human Gut Microbiome by Dr. Mark Pimentel To aid readers, Clinical Understanding of the Human Gut Microbiome integrates a variety of human gut microbiome research so that physicians and clinicians can then make the best decisions in the care of their patients. BUY IT HERE

The Microbiome Connection by Dr. Mark Pimentel Your Guide to IBS, SIBO, and Low-Fermentation Eating  BUY IT HERE

Healing SIBO by Shivan Sarna Half Book, Half Cookbook (+ vegetarian SIBO recipes) "very organized, full of insight, painstakingly researched, highly practical and imbued with warm-hearted fun" - Dr. Sandberg-Lewis BUY IT HERE

SIBO Made Simple by Phoebe Lapine Half Book, Half Cookbook Offers a clear path forward, from someone who's been there. BUY IT HERE

Direct-to-Consumer
Lactulose SIBO Tests

Patients (and practitioners without prescription rights) can order Lactulose Breath Tests directly.

 

RUPA Labs - SIBO Tests
Also available are: IBS-Smart, Trio-Smart, stool, mold, leaky gut and other functional medicine tests.
 Rupa Labs Test Menu - order here   

TRUE HEALTH Labs - SIBO Test
U.S. (all states), Canada & Europe
Also available are: stool, mold, leaky gut and other functional medicine tests.
True Health Labs - order here

 

 

Learn more about SIBO Testing HERE
Watch my SIBO Testing Masterclass HERE

 

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Dr. Siebecker's SIBO Courses

Join me!
Expert SIBO knowledge at your fingertips! With live Q&A case discussions.

And an AI search tool which can answer your questions asap, without having to watch all the classes.
 (full Pro course and Patient course).

 

PATIENTS - SIBO Recovery Roadmap Course

PRACTITIONERS

• SIBO Pro Course (22 hours - 20 CME)
  
  
• SIBO Pro MINI-Course (3.5 hours) 
  
  
• SIBO Diagnosis and Testing MINI-Course (3 hours)
  

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       SIBO PODCASTS     

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Gastro Girl SIBO and IMO: Understanding Gut Overgrowth, Methane, and Archaea with Dr. Mark Pimentel     Check out other recent episodes Here

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Dr. Ruscio Radio Top 5 NEW SIBO Treatment Facts You Need To Know in 2025 with Dr. Ruscio      Check out other recent episodes Here

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Dr. Allison Siebecker | SIBO Info The Mystery of SIBO & Silent Sinusitis with Dr. Douglas Skarada with Dr. Skarada How Probiotics Healed Her SIBO: Real Results & Proven Protocol with Lindsey Wismer NP Elemental Diet Success for SIBO & Beyond with Dr. Roy & Debbie Steinbock Yes, SIBO Treatment Really Does Work! with Dr. Siebecker Check out other recent episodes Here

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Check out these other Podcasts for more SIBO related info 

• The Healthy Gut Podcast - Rebecca Coomes
• The SIBO Doctor Podcast - Nirala Jacobi
• The Turd Nerds
• The Rational Wellness Podcast - Dr. Ben Weitz
• Lynda Griparic 
• SIBO Made Simple Podcast
• Healthpath
• REVOLUTION HEALTH - Chris Kressor
• FUNK'TIONAL NUTRITION PODCAST
• The Emoroid Digest Podcast
• The Gut Connection Podcast
• Happy Bones, Happy Life Podcast
  
• The healthy Skin Show
• THIS ENDOLIFE PODCAST
• Holistic Health Habits Podcast!
• Gut Feeling with Dr Pal - Podcast
• A Little Bit Healthier 
• THE EXPERTS' CORNER
• Dr. Ruscio Radio
• Gastro Girl

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           HOT OFF THE PRESS         

SIBO studies published in the last 3 months

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Causes/ Risk Factors

Dyssynergic Defecation

• Dyssynergic Defecation Is Associated With Small Intestinal Bacterial Overgrowth.  PMID: 41204444 
  • Summary: "We found that pelvic floor dysfunction is associated with microbial overgrowth, especially Intestinal Methanogen Overgrowth!" John Damianos via X

Surgery

• Alterations in Gut Microbiota After Upper Gastrointestinal Resections: Should We Implement Screening to Prevent Complications?  PMID: 41155808

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Pathophysiology

• Evaluating the Clinical Relevance of Elevated Mucosal Mast Cells in the Gastrointestinal Tract. PMID: 41474636

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Associated Conditions

Brain Fog

• Brain Fog in Gastrointestinal Disorders: Small Intestinal Bacterial Overgrowth, Gastroparesis, Irritable Bowel Syndrome.  PMID: 39495803

Cancer and  Causes: Surgery:

• Prevalence and Impact on Quality of Life of Small Intestinal Bacterial Overgrowth (SIBO)-Related Symptoms in Patients with Upper Gastrointestinal Cancer. PMID: 41439939

Children

• Small Intestinal Bacterial Overgrowth in Children with Short Bowel Syndrome.  PMID: 41300666
• Intestinal methanogen overgrowth and its impact on gastrointestinal disorders in children: a retrospective study.  PMID: 41316018
  • Summary: “IMO positivity is prevalent in children with gastrointestinal symptoms, particularly prominent among those with FGID [functional GI disorders]. The IMO positive group exhibited a lower incidence of diarrhea and more frequently demonstrated terminal ileal villous blunting.”

Chronic Intestinal Pseudo-Obstruction

• Hydrogen-Positive Small Intestinal Bacterial Overgrowth (SIBO) in Japanese Patients With Chronic Intestinal Pseudo-Obstruction (CIPO): A Cross-Sectional Study.  PMID: 41209870

Dyssynergic Defecation NEW

• Dyssynergic Defecation Is Associated With Small Intestinal Bacterial Overgrowth.  PMID: 41204444 
  • Summary: "We found that pelvic floor dysfunction is associated with microbial overgrowth, especially Intestinal Methanogen Overgrowth!" John Damianos via X

Gastric Bypass

• Alterations in Gut Microbiota After Upper Gastrointestinal Resections: Should We Implement Screening to Prevent Complications?  PMID: 41155808

GERD

• Association of gastroesophageal reflux disease with small intestinal bacterial overgrowth: a case-control study.  PMID: 41131458

• Clinical utility of small intestinal bacterial overgrowth (SIBO) testing in guiding management of gas-bloat symptoms after antireflux surgery.  PMID: 40877632
  

Gu Syndrome NEW

• Self-Directed Recovery of Gu Syndrome: Reversal of Multisystem Dysfunction via Microbiome Restoration and Subconscious-Guided Protocols.  PMID: 41246705

Halitosis

• Therapeutic effect of the low FODMAPs diet for refractory halitosis associated with small intestinal bacterial overgrowth.  PMID: 40992384

IBS   

• Ileal Biofilms Confirm SIBO-IBS Hypothesis: Comment on PMID 38798120.  PMID: 41133378
• Response to Maximilian and Gasche.  PMID: 41102925
• Survey of Latin American gastroenterologists, specialists in disorders of gut-brain interaction, on the diagnosis and treatment of irritable bowel syndrome in clinical practice.  PMID: 41111058

Lactose Intolerance

• Response to V. Martín-Dominguez Et Al.: Re-Evaluating the Diagnostic Approach to Lactose Malabsorption.  PMID: 41319163

Pancreatitis

• Gastrointestinal Symptom Burden After Total Pancreatectomy with Islet Autotransplantation, A Prospective Observational Cohort Study.  PMID: 41172147
  

PPI

• Proton pump inhibitors are not associated with an increased risk of Clostridioides difficile infection: a systematic review and meta-analysis of randomized controlled trials.  PMID: 41047657

Restless Legs Syndrome

• Analysis of gut microbiota in Restless Legs Syndrome: searching for a metagenomic signature.   PMID: 41378921

Rosacea

• The exposomal imprint on rosacea: More than skin deep.  PMID: 41081484
  

Scleroderma

• Nutritional Status and Dietary Challenges in Patients with Systemic Sclerosis: A Comprehensive Review.  PMID: 41097221
• Prevalence, clinical characteristics, and hospital course of systemic sclerosis-associated pseudo-obstruction.  PMID: 41032167

Short Bowel Syndrome

• Small Intestinal Bacterial Overgrowth in Children with Short Bowel Syndrome.  PMID: 41300666

SIFO

• Self-Directed Recovery of Gu Syndrome: Reversal of Multisystem Dysfunction via Microbiome Restoration and Subconscious-Guided Protocols.  PMID: 41246705
  

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Testing

• Frequent errors in the interpretation of breath tests in patients with suspected small intestinal bacterial overgrowth (SIBO).  PMID: 40503974
• Implementation of a digital tool to assist physicians during breath tests for SIBO: Impact on diagnostic accuracy, report quality and physician workload.  PMID: 41110827
• Response to V. Martín-Dominguez Et Al.: Re-Evaluating the Diagnostic Approach to Lactose Malabsorption.  PMID: 41319163
• Hypersensitivity to the lactulose nutrient challenge test in irritable bowel syndrome - a non-invasive test of meal-related symptoms.  PMID: 41247041
• Evacuation Dysfunction Does Not Impact Breath Test Results. PMID: 41388564
• Diagnostic Evaluation of Small Intestinal Microbial Overgrowth: A Cross-Sectional Comparison of Glucose and Lactulose Breath Tests. PMID: 41464822 Free PMC article.

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Methane

• Intestinal methanogen overgrowth and its impact on gastrointestinal disorders in children: a retrospective study.  PMID: 41316018
  • Summary: “IMO positivity is prevalent in children with gastrointestinal symptoms, particularly prominent among those with FGID [functional GI disorders]. The IMO positive group exhibited a lower incidence of diarrhea and more frequently demonstrated terminal ileal villous blunting.”

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Treatment

• Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth.  PMID: 41394228
  • Summary: new article from my friend Michael Ruscio
     “Adding a biofilm disruptor to herbal antimicrobials was associated with significantly greater reductions in hydrogen and methane gas levels. Larger prospective, controlled studies are needed to validate these findings and clarify the potential role of biofilm disruptors in the management of SIBO/IMO.”
• Comparative efficacy of diverse therapeutic regimens for small intestinal bacterial overgrowth: a systematic network meta-analysis. PMID: 41394885

Antibiotics

• Clinical Trial: Rifaximin Versus Low FODMAP Diet in Irritable Bowel Syndrome.  PMID: 41098003
  • Summary: “rifaximin led to significantly earlier individual symptom improvement [vs. Low FODMAP Diet] at Week 2, including global symptoms (90.0% vs. 72.0), bloating (84.0% vs. 58.0%) and abdominal pain (80.0% vs. 58.0%).
    
  • “SIBO eradication was observed in 63.6% (rifaximin) and 50.0% (LFD). Adherence was significantly better with rifaximin (95.9% vs. 77.8%
• Impact of four-week rifaximin treatment on abdominal symptoms, psychological state and gut microbiome in diarrhea-predominant irritable bowel syndrome: a pilot study.  PMID: 41110752
  
• Rifaximin improves anxiety- and depression-like behaviors in rats by regulating NPY in the colon and mPFC.  PMID: 41430083
  • Summary: In an animal model, rifaximin has an anti-anxiety and anti-depressant effect.
    “its mechanism may be related to the rifaximin's regulation on NPY [neuropeptide Y] mediated gut-brain axis between colon and mPFC [medial prefrontal cortex in the brain].

Herbal Antibiotics

• Chronic administration of berberine attenuates depressive-like behavior in rats subjected to chronic unpredictable mild stress combined with ACTH treatment: Role of nitrergic system. PMID: 41429409
  • Summary: animal model - “berberine treatment may exert its antidepressant-like and memory-enhancing effects, at least in part, by attenuating hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, potentially through the involvement of nitrergic signaling.”

Diet

• The Mediterranean Diet for Irritable Bowel Syndrome : A Randomized Clinical Trial.  PMID: 41144975

Fecal Micobiota Transplantation (FMT)

• Advances in capsule-based fecal microbiota transplantation: clinical applications and innovations.  PMID: 41331614

Probiotics

• Probiotic Blend of Lactobacillus acidophilus LA-5 and Bifidobacterium animalis ssp. Lactis BB-12 in Non-constipated Irritable Bowel Syndrome: A Double-Blind Randomized Placebo-Controlled Trial.  PMID: 41255078

Prokinetics

• Iberogast in functional dyspepsia: yesterday, today, and tomorrow - a narrative review of a multitarget phytomedicine.  PMID: 41319263
  • Summary: “Iberogast remains an evidence-based phytomedicine with a favorable safety profile, filling therapeutic gaps in FD by targeting motility, hypersensitivity, inflammation, and barrier function.”
• Effect of STW 5-II (Iberogast-N) on Tolerance to Gastric Gas in Patients With Functional Dyspepsia. The IBO-2 Study.  PMID: 40684457
  • Summary: Gas was infused into the stomach of dyspepsia and bloating patients - gas evacuation was faster and gas retention was less in those on Iberogast.

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Diet FODMAP

• Therapeutic effect of the low FODMAPs diet for refractory halitosis associated with small intestinal bacterial overgrowth.  PMID: 40992384
• Clinical Trial: Rifaximin Versus Low FODMAP Diet in Irritable Bowel Syndrome.  PMID: 41098003
  • Summary: “rifaximin led to significantly earlier individual symptom improvement [vs. Low FODAM Diet] at Week 2, including global symptoms (90.0% vs. 72.0), bloating (84.0% vs. 58.0%) and abdominal pain (80.0% vs. 58.0%).
    
  • “SIBO eradication was observed in 63.6% (rifaximin) and 50.0% (LFD). Adherence was significantly better with rifaximin (95.9% vs. 77.8%
• Impact of Short Duration FODMAP Restriction on Breath Gases and Gastrointestinal Symptoms.  PMID: 40622403
• Impact of low-FODMAP diet on symptom relief in irritable bowel syndrome patients.  PMID: 41338949
• Modification of the Low FODMAP Diet Is Feasible in the Treatment of Irritable Bowel Syndrome: A Randomised Crossover Study.  PMID: 41278484 Free PMC article.
• Development and Validation of a Self-Administered Simplified Food Frequency Questionnaire for FODMAP Intake Evaluation (FFQ-FODMAP-BE).  PMID: 41091284
• Implementing a Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Diet in Asia: Addressing Cultural, Clinical and Practical Challenges.  PMID: 41077745 Free
• Targeting Irritable Bowel Syndrome Through Diet and Mechanism-Based Therapies: A Pathophysiological Approach.  PMID: 41305645
• An online low-FODMAP educational intervention improves physical and psychological symptoms of irritable bowel syndrome. PMID: 41406439
• A study on the utility of inflammatory biomarkers in primary care irritable bowel syndrome: a sub analysis of the DOMINO randomized trial. PMID: 41436948

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Related

• Real-World Evidence of the Long-Term Clinical Utility of a Vibrating Capsule in the Management of Chronic Idiopathic Constipation.  PMID: 40920213
  • Summary: Frequency, stool consistency, and straining improved.
    “VC [vibrating capsule] seems both effective and safe for long-term treatment of chronic constipation with diarrhea being notably uncommon. 4.6%…reported feeling a sensation of vibration, 1.8% reported abdominal pain and 0.64% reported diarrhea.”>Vibrant Gastro

 

Check out all the SIBO research on SIBOinfo.com:
Studies and Associated Diseases  

 

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NOT TO BE MISSED! 

Did you miss an email or event in the past 3 months? Here's what happened:

• Check out the new look and lots of new information on my website siboinfo.com
• The Mystery of SIBO & Silent Sinusitis Click here to watch
• Elemental Diet Success for SIBO & Beyond Click here to watch
• How Probiotics Healed Her SIBO: Real Results & Proven Protocol Click here to watch