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SIBO RESOURCES from Dr. Siebecker
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Click a button above for the latest SIBO Podcasts, Studies and Events
15-20% Off Supplements at Fullscript (U.S.)
Fullscript carries over 20,000 professional-grade supplements and body care items. FSA and HSA accounts can be used. Feel free to share the link with friends and family! U.S. only.
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Once logged in, see "Community Plans" or "Favorites" for lists of my favorite SIBO supplements.
Dr. Siebecker's Most Recent Quarterly Newsletter
July 2025
SIBO CLASSES + EVENTS
SIBO INFO WEBSITE UPDATE
As of Aug 30 there is a new look and lots of new information on my website siboinfo.com
I added 8+ new pages, a free dessert mini-cookbook and fancy new info-graphics!
What's new:
- A search bar (footer and top right of all pages) - type in what your looking for!
- My SIBO Dessert Recipes (halfway down the Home page)
- Underlying Causes
- SIBO and IBS
- Updated Testing info (with interpretation and ordering help)
- Treatment
- How to Treat SIBO (including common mistakes)
- Symptom Relief (with detailed probiotic info and shopping links)
- What to Avoid
- My specific Antibiotic and Herbal Antibiotic Protocols and Dosage (with sign in)
- Updated Prokinetic & Prevention info
- PROBIOTICS for SIBO!
- New Resources: Discount codes
- including a new incredible Allimed deal - 100 caps for $79.50! (no code needed) (trusted source)
- including a new incredible Allimed deal - 100 caps for $79.50! (no code needed) (trusted source)
SIBOINFO IS UPDATED - CHECK IT OUT!
Note: if you tried to download the Dessert Recipes - it's available now. Log in here to download.
Q&A with Dr. Allison Siebecker
October 23
as part of my new SIBO & IBS Support Membership
Shivan Sarna and I have created a SIBO Support Program! We want to help!
Here's what's included:
1) Every MONTH, a live Q&A session with Dr. Siebecker - I will be there to answer your questions every single month!
2) 20% Supplement Discount at Fullscript on 20,000+ professional-grade supplements (this alone could cover the entire membership cost!)
3) SIBO Smart Search - an AI version of Dr. Siebecker answers your questions 24/7!
- It's absolutely amazing - Watch a Quick Demo Video Here (SIBO Smart Search)
- This offers ongoing, around the clock SIBO Support!
4) A bunch more:
- Access to an extensive library of SIBO masterclasses
- including Dr. Siebecker’s Masterclasses on Diet, Testing, Treatment, Tough Cases and more
- SIBO Recovery Roadmap® Course (my SIBO course for patients - a complete SIBO DIY, $499 value)
- Dr. Siebecker's proven 9-step SIBO healing protocol
- SIBO-friendly Recipe Exchange
MEMBERSHIP Q&A OCTOBER 23 - JOIN HERE
FREE WEBINAR
Elemental Diet Success for SIBO & Beyond
with Dr. Roy & Debbie Steinbock
October 30th, 11:00am PT/ 2pm ET
Shivan and I will be hosting Dr. Roy and Debbie Steinbock, to talk about their experience with Elemental Diet and SIBO.
They have guided thousands through this medical food protocol that outperforms every pharmaceutical option for SIBO.
They've seen it work for hydrogen, methane, AND hydrogen sulfide SIBO, even in cases where multiple antibiotic rounds failed.
REGISTER NOW - Get instant access to "5 Tips to Elemental Diet Success" Guide
The Steinbocks will discuss their proven 3-step system that makes elemental diet not just doable, but surprisingly straightforward.
Practitioner Q&A with Dr. Allison Siebecker
November 18th
as part of my SIBO Pro Course
I love answering your questions, including helping with your SIBO cases.
We have an amazing group of practitioners who attend and share ideas (think tank!) - join us!
Pro Course Q&A and More Info
NEW - Now with AI Smart Search
Ask your questions anytime 24/7 and it answers based on the course materials.
You can online-chat or call it for a verbal conversation - it sounds like me and asks questions back.
Get your answers in seconds. It is absolutely amazing!
GASTRO ANP CONFERENCE RECORDING AVAILABLE
We had an incredible conference this past weekend and it's not too late to watch it.
The recording is available until October 20th.
It's my favorite GI conference!
GASTRO ANP CONFERENCE RECORDING - ENROLL HERE
Congratulations to my friend and colleague Dr. Mark Davis (pictured far right) who won the Lifetime Achievement Award from the Gastroenterology Association of Naturopathic Physicians this year.
GastroANP Lifetime Achievement Award winners:
Steven Sandberg-Lewis (2019), Lela Altman (2024), Mona Morstein (2023), Ilana Gurevich (2022), Allison Siebecker (2021), Mark Davis (2025).
[Eric Yarnell (2020) not pictured]
RESEARCH UPDATES & NEWS
> Generic Motegrity (Prucalopride) is available in the U.S. from ANI Pharmaceuticals, as of January 2025. Prucalopride is used in low-dose (0.5-1mg) for SIBO relapse prevention.
> From Dr. Pimentel on X:
Jul 12: "Today @TheEndoSociety our team from @MASTprogram @CedarsSinai shows in presentation that #hypothyroidism is associated with a unique type of #SIBO (more Klebsiella) and confirms that hypothyroidism may be a precursor to SIBO based on TriNetX data."
"Interestingly, autoimmune hypothyroidism had an even stronger association with #SIBO"
Jul 14: "Today @TheEndoSociety we are presenting data that adding Rothia mucilaginosa to the gut induces a #PCOS phenotype and the metabolic changes return to normal after stopping Rothia."
[endometriosis is an underlying cause of SIBO]
Jul 17: "September will be the 5th anniversary of @MASTprogram in our current location. It continues to be a privilege to work towards helping patients who suffer. We will post some of the amazing highlights from the past 5 years over the coming weeks."
Jul 23: "It now seems obvious but a great deal of work went into understanding the role of #methane and #constipation now called #IMO, setting up new drug therapy. Here we present the cause and effect evidence for methane causing constipation from @MASTprogram @CedarsSinai #theMAST5years"
Jul 25: "Haven't done a poll in a while. If you have #IBS-diarrhea, which symptom is your most bothersome?
- Abdominal pain 21.4%
- Bloating 41.9%
- Diarrhea 36.8%
"Shocking...not shocking! Bloating is #1 one and pain 3rd in IBS-D patients. That's what I hear every day. Yet the criteria don't even include bloating...ridiculous. As a result, bloating cannot be a primary or secondary endpoint for drug trials. We need to listen to patients."
Jul 31: "I feel like another poll. Please share this one because it's important. Those with any kind of IBS or functional gut disorder, have you ever been told to "relax" and "not worry so much (It's just IBS)"?
- Yes 86%
- No 14%

SIBO RESOURCES
Dr. Siebecker's You Tube
I post weekly videos and interviews about SIBO and related topics.
If you search for my channel by name at YouTube - Dr. Allison Siebecker | SIBO INFO, it will greatly help my videos be shown to more people that could benefit (thanks!).
I post weekly videos and interviews about SIBO and related topics.
If you search for my channel by name at YouTube - Dr. Allison Siebecker | SIBO INFO, it will greatly help my videos be shown to more people that could benefit (thanks!).
Allimed Discount!
450mg Allicin/cap, 100 caps for $79.50
that's 56% off standard retail!
(no code needed - trusted source)
Free Shipping (U.S. shipping only)
15% Supplement Discount
at Fullscript
20% with my SIBO Membership Program
Fullscript carries 20,000+ high-quality professional supplements, and natural body care, from over 300 brands.
Discount is automatically applied at checkout to everything at Fullscript.
(FSA and HSA accounts can be used.)
To see my favorite SIBO supplements, see "Community Plans" or "Favorites".
Feel free to share with friends and family. :)
NEW Prokinetics!
Biocidin "Motility Assist"
(with ginger and triphala)
Motility Assist - 15% Off at Fullscript
and
Biotics "Motility-Zyme"
(with ginger, artichoke and 5-HTP)
Motility-Zyme - 15% Off at Fullscript
NEW ELEMENTAL DIETS
New Flavor Alert
Vanilla Coconut
ElementAll - 15% off at Fullscript
Elemental Diet Powder
Use code SIBO50 for $50 off, or SIBO for $25 off (one time use)
Published mBIOTA success rates for SIBO: 100% Hydrogen SIBO; 75% Methane + Hydrogen, 58% Methane SIBO/IMO.
Check out my recent discussion with Dr. Rezaie on mBiotia results (about 1/3 of the way into the interview)
... and learn what hibernating bears have to do with the Elemental Diet and SIBO!
Elemental Diet Ordering
Some elemental diets are available only through a practitioner.
However, patients can order the following Elemental Diets themselves, via:
1. Functional Medicine Formulations
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● Elemental Heal Whey Free (elemental diet)
● Elemental Heal (semi-elemental) - add oil separately
● Elemental Heal Low Carb (semi-elemental) - add oil separately
● MCT Oil powder - to add to semi-elemental diets above
Use code ALLISON15 for 15% off
(discount code applies to all supplements they carry)
2. My Fullscript Dispensary (15% off)
● Integrative Therapeutics: Physicians Elemental Diet and Physicians Elemental Diet Dextrose-Free
● Bioclinic Naturals: ElementAll
● Vita Aid: Elemental Nutrition and Keto-Elemental Nutrition
No Code needed - discount is automatically applied to everything at Fullscript.
SIBO Books
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Clinical Understanding of the
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The Microbiome Connection byDr. Mark Pimentel
Your Guide to IBS, SIBO, and Low-Fermentation Eating |
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SIBO Made Simple by
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SIBO Cookbooks
SIBO Summer Cookbook |
SIBO Soups eCookbook |
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Full of recipes that are perfect for the warmer summer months. |
40 delicious, affordable and easy to make soup recipes. |
SIBO Family Favourites Cookbook |
SIBO Holiday Cookbook |
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A range of recipes the whole family will love: American, Australian and Asian classics. |
Don’t feel deprived in the holiday season! |
Direct-to-Consumer SIBO Tests
Patients (and practitioners without prescription rights) can order Lactulose Breath Tests directly.
RUPA Labs - SIBO Tests
Also available are: IBS-Smart, Trio-Smart, stool, mold, leaky gut and other functional medicine tests.
Rupa Labs Test Menu - order here
TRUE HEALTH Labs - SIBO Test
U.S. (all states), Canada, Europe
Also available are: stool, mold, leaky gut and other functional medicine tests.
True Health Labs - order here
Learn more about SIBO Testing HERE
Watch my SIBO Testing Masterclass HERE
TRUE HEALTH Labs
U.S. (all states), Canada
Also available are stool, mold, leaky gut and other functional medicine tests.
True Health Labs - order here
Learn more about SIBO Testing HERE
Watch my SIBO Testing Masterclass HERE
Dr. Siebecker's SIBO Courses
A veritable wealth of knowledge at your fingertips, plus live Q&A case discussions. Join me!
PATIENTS - SIBO Recovery Roadmap Course
PRACTITIONERS
- SIBO Pro Course (22 hours - 20 CME)
- SIBO Pro Mini-Course (3.5 hours)
- SIBO Diagnosis and Testing Mini-Course (3 hours)
SIBO PODCASTS
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Funk'tional Nutrition Podcast Why Your SIBO Keeps Coming Back: The Overlooked Root Causes of Recurring SIBO & Bloating with Erin Holt
Check out other recent episodes Here
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Dr. Ruscio Radio This Top Treatment Heals SIBO, IBD & Autoimmune Disease with Dr. Ruscio The Top 3 Diet Plans For SIBO, Candida & Histamine Intoleranc with Dr. Ruscio SIBO & Histamine Intolerance with Dr. Ruscio
Check out other recent episodes Here
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The Healthy Gut Pelvic Tightness, Pelvic Pain & SIBO with Dr Meg Withers Check out other episodes Here |
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THIS ENDOLIFE PODCAST IS THE LOW FODMAP DIET HELPFUL FOR THOSE WITH BOTH ENDO AND SIBO? with Jessica Duffin
Check out other recent episodes Here |
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The Turd Nerds Summer replay - Treatment options for SIBO varieties - SIBO part 2 with Dr. Rebecca Sand Summer replay - SIBO - pathology and testing with Drs. Rebecca Sand, Ilana Gurevich, Ami Kapadia
Check out other recent episodes Here |
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Dr. Allison Siebecker | SIBO Info FoodMarble SIBO Test Update (PPM's for all) with Claire Shortt New SIBO & IBS Research + Q&A with Dr. Mark Pimentel SIBO Updates and Q&A with Dr. Ali Rezaie Post-Biotics for GI Health with Dr. Andrea McBeth Check out other recent episodes Here |
Check out these other Podcasts for more SIBO related info
- The Healthy Gut Podcast - Rebecca Coomes
- The SIBO Doctor Podcast - Nirala Jacobi
- The Turd Nerds
- The Rational Wellness Podcast - Dr. Ben Weitz
- Lynda Griparic
- SIBO Made Simple Podcast
- Healthpath
- REVOLUTION HEALTH - Chris Kressor
- FUNK'TIONAL NUTRITION PODCAST
- The Emoroid Digest Podcast
- The Gut Connection Podcast
- Happy Bones, Happy Life Podcast
- The healthy Skin Show
- The Endo Belly Coach
- Holistic Health Habits Podcast!
- Gut Feeling with Dr Pal - Podcast
- A Little Bit Healthier
HOT OFF THE PRESS
SIBO studies published in the last 3 months
Studies from the annual GI conference Digestive Disease Week held in May, are included below (listed in all caps without a PMID #). They are so hot off the press, they haven't been published in full article format, and may never be!
Overview
- Modern concepts of small intestinal bacterial overgrowth. PMID: 40960427
- Summary: Newest overview of SIBO, written by Dr. Mark Pimentel
Causes/ Risk Factors
Drugs
GLP-1 NEW
- Diagnostic Evaluation of an Increased Risk of Developing Small Intestinal Bacterial Overgrowth Associated with Glucagon-like Peptide-1 (GLP-1) Receptor Agonists and Dual GLP-1/GIP Receptor Agonists: A Global Retrospective Multicenter Cohort Analysis. PMID: 40941750
- Summary: this is the first large-scale study to identify an increased incidence of SIBO associated with GLP-1/GIP diabetes medications [Ozempic, Mounjaro]. The risk is associated with longer-term use (1 year).
- GLP-1 Receptor Agonist Use Is Associated with Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth. DOI: https://doi.org/10.1177/26345161251353437
- Summary: “GLP1RA use is associated with SIBO, although diabetes may be a confounder.”
PPI
- Clinical utility of small intestinal bacterial overgrowth (SIBO) testing in guiding management of gas-bloat symptoms after antireflux surgery. PMID: 40877632
- Pharmacodynamics, pharmacokinetics, interactions with other drugs, toxicity and clinical effectiveness of proton pump inhibitors. PMID: 40771914
- The Duration of Proton Pump Inhibitor Therapy and the Risk of Small Intestinal Bacterial Overgrowth: A Systematic Review and Meta-Analysis. PMID: 40649078
- Summary: “PPI use significantly increases the risk of SIBO, with longer treatment durations associated with higher odds … each additional month of PPI therapy was associated with a 4% increase in SIBO risk.”
- Summary: “PPI use significantly increases the risk of SIBO, with longer treatment durations associated with higher odds … each additional month of PPI therapy was associated with a 4% increase in SIBO risk.”
Pathophysiology
- Small intestine bacterial overgrowth breath test does not predict symptom severity in gut-brain interaction disorders: role of anxiety, depression and inflammatory biomarkers. PMID: 40276984
- Summary: “Abdominal pain correlated with levels of histamine and ghrelin, while abdominal distension correlated with I-FABP levels [intestinal-fatty acid binding protein].”
Associated Conditions
Children
- Small intestinal bacterial overgrowth in children: An expert review by the ESPGHAN Gastroenterology Committee. PMID: 40731137
- Enhancing pediatric practice: A comprehensive review on malabsorption in pediatrics for diagnostic and management approach. PMID: 40769093
- Exploring small intestinal bacterial overgrowth in functional upper gastrointestinal disorder: A comprehensive case-control study. PMID: 40881097
GERD
- Can Symptoms and Medical History Predict Outcomes for Hydrogen and Methane Breath Testing? PMID: 40788605
- The Lactulose Breath Test can Predict Refractory Gastroesophageal Reflux Disease by Measuring Bacterial Overgrowth in the Small Intestine. PMID: 406898
HIV
- Gastrointestinal Dysmotility, Autonomic Function, and Small Intestinal Bacterial Overgrowth Among People With Well-Controlled HIV. PMID: 40358243
Hypertension (High Blood Pressure)
- Small intestinal bacterial overgrowth as one of the diagnostic markers of hypertension. PMID: 40813611
Hypothryroid
- Relationship between hypothyroidism, risk of small intestinal bacterial overgrowth, and duodenal microbiome alterations. PMID: 40908532
- Summary: “SIBO prevalence was higher in the hypothyroid group (32.65%) vs. controls (15.17%).”
- From "Research Update" section above: “SIBO associated with hypothyroidism may be of a different phenotype than the SIBO in other patients.” And “bacteria found in subjects with hypothyroidism + SIBO differ from those with #SIBO alone, suggesting unique microbial signatures between the two groups” - Dr. Pimentel and Dr. Wei
IBD
- [Clinical features of ulcerative colitis in patients with small intestinal bacterial overgrowth]. PMID: 40764120
Intestinal Failure
- Small intestinal bacterial overgrowth and dysbiosis in children with intestinal failure: A descriptive cohort study. PMID: 40722249
IBS
- Can Symptoms and Medical History Predict Outcomes for Hydrogen and Methane Breath Testing? PMID: 40788605
- The evolution of irritable bowel syndrome as a group of organic diseases: a narrative review. PMID: 40823787
- Summary: “Although existing symptom-based diagnostic criteria for IBS have been useful, they have contributed to a situation whereby current treatments address symptoms, not the underlying causes. Approaching IBS as a constellation of diseases with individual organic bases will allow the development of more precisely targeted and effective treatments.” Amen!
Mood Disorders
- Small intestine bacterial overgrowth breath test does not predict symptom severity in gut-brain interaction disorders: role of anxiety, depression and inflammatory biomarkers. PMID: 40276984
- Summary: “Abdominal pain correlated with levels of histamine and ghrelin, while abdominal distension correlated with I-FABP levels [intestinal-fatty acid binding protein].”
Pancreatitis
- The intricate interplay between acute pancreatitis and small intestinal bacterial overgrowth: Unraveling the unknown. PMID: 40664102 Review.
Parkinson’s Disease
Rosacea
- [Prevalence and risk of small intestinal bacterial overgrowth in patients with rosacea: A systematic review and meta-analysis]. PMID: 40778919
- Summary: There is a 3.5 x higher risk of developing SIBO in patients with rosacea
Scleroderma
- The efficacy of probiotics, prebiotics or synbiotics in scleroderma: A systematic review. PMID: 40311922
- Anti-cytolethal distending toxin antibodies in systemic sclerosis: associations with gastrointestinal disease and immune dysregulation. PMID: 4063769
Treatment
Antibiotics
- [Study on the efficacy of combination therapy with rifaximin and Saccharomyces boulardii CNCM I-745 in patients with small intestinal bacterial overgrowth associated with long-term use of proton pump inhibitors]. PMID: 40884341
- Summary: Florastor (Saccharomyces boulardii CNCM I-745) + Rifaximin was more effective than Rifaximin alone for SIBO eradication, symptom relapse, and quality of life, in patients with PPI-associated SIBO.
- Lycium barbarum Glycopeptide Alleviates Neomycin-Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase-Mediated Serotonin Biosynthesis. PMID: 40135846
- Lycium barbarum is also known as goji berries
Herbal Antibiotics
- Therapeutic effects of olive leaf tea (Olea europaea L.) on gastrointestinal symptoms and body composition in adults with small intestinal bacterial overgrowth. PMID: 40917089
- Summary: 2 months of olive leaf tea (1.7 g leaf powder/250 mL hot water x 7-10 minutes) 2 x day, had a significant decrease in symptoms, gas peak and mean levels (hydrogen and methane), with 88% glucose test normalization rate.
- Summary: 2 months of olive leaf tea (1.7 g leaf powder/250 mL hot water x 7-10 minutes) 2 x day, had a significant decrease in symptoms, gas peak and mean levels (hydrogen and methane), with 88% glucose test normalization rate.
Probiotics
- [Study on the efficacy of combination therapy with rifaximin and Saccharomyces boulardii CNCM I-745 in patients with small intestinal bacterial overgrowth associated with long-term use of proton pump inhibitors]. PMID: 40884341
- Summary: Florastor (Saccharomyces boulardii CNCM I-745) + Rifaximin was more effective than Rifaximin alone for SIBO eradication, symptom relapse, and quality of life, in patients with PPI-associated SIBO.
Prokinetics
- Mechanistic Insights Into Prucalopride's Role in Irritable Bowel Syndrome Treatment: Schwann-like Enteric Glial Cells as Therapeutic Targets. PMID: 40609660
- Summary: “the findings…suggest that prucalopride may act on Schwann-like enteric glial cells to promote neurogenesis, thereby restoring neuronal populations and potentially modulating visceral sensitivity. This regenerative effect offers a comprehensive therapeutic approach for IBS, targeting not only motility dysfunction but also underlying neuronal deficits.”
Diet
- Unlocking the potential of the low FODMAP diet: comprehensive insights into clinical efficacy, microbiome modulation, and beyond. PMID: 40497754
- Assessing the Impact of the Low-FODMAP Diet on IBS Management in Asian Countries: A Systematic Review and Meta-Analysis of Evidence. PMID: 40715773
- Low FODMAP Diets in Populations with IBS: Modifying Western Concepts to Eastern Populations. PMID: 40913725
- Impacts of the Long-Term Low-FODMAP Diet in Patients With Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. PMID: 40735813
- A 12-Week Strict Low FODMAP Diet Reduces the Severity Levels of Fatigue, Depression, Anxiety, and Inattention in Patients with Irritable Bowel Syndrome. PMID: 40654377
- Increase in circulating GLP-1 following low FODMAP diet in irritable bowel syndrome patients. PMID: 40880735
- Summary: In IBS patients, a 12-week low FODMAP diet, decreased IBS symptoms and body weight, and increased GLP-1 levels (from average 3.3 pM to 3.6 pM).
- Impact of Short Duration FODMAP Restriction on Breath Gases and Gastrointestinal Symptoms. PMID: 40622403
- Summary: 1-week low FODMAP diet reduced bloating, abdominal pain, flatulence, methane and hydrogen.
- Effects of Probiotics and Diet Management in Patients With Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis. PMID: 39862384
- Dietary Intake, Symptom Control and Quality of Life After Dietitian-Delivered Education on a FODMAP Diet for Irritable Bowel Syndrome: A 7-Year Follow Up. PMID: 40589416
- Dietary fermentable polyols fuel gut inflammation through M1 macrophage polarization and gut microbiota. PMID: 40678521
- The Ten Dietary Commandments for Patients with Irritable Bowel Syndrome: A Narrative Review with Pragmatic Indications. PMID: 40806081
- Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome-A randomized, double-blind, placebo-controlled trial. PMID: 40693198
- Remission of irritable bowel syndrome with lifestyle medicine. PMID: 40735575
- Microwave irradiation benefits fructan degradation in sourdough steamed cake by tunning the β-fructosidase FosE-substrate interaction. PMID: 40120306
- Summary: Microwave heating activates β-fructosidase FosE enzyme in sourdough cake, which breaks down Fructans (lowering the fructan amount of sourdough). This enzyme is secreted by L. paracasei in sourdough.
Related
- European Consensus on Functional Bloating and Abdominal Distension-An ESNM/UEG Recommendations for Clinical Management. PMID: 40844856
- Irritable Bowel Syndrome. PMID: 30521231
- Irritable Bowel Syndrome. PMID: 40789179
- Common misconceptions and controversies in the management of irritable bowel syndrome. PMID: 40281279
Check out all the SIBO research on SIBOinfo.com:
Studies and Associated Diseases
NOT TO BE MISSED!
Did you miss an email or event in the past 3 months? Here's what happened:
- Masterclass: Aging Well: The Microbiome Method with Dr. Jason Hawrelak - Click Here
- Masterclass: Gut Microbiome Healing: Postbiotic Revolution with Drs. Andrea McBeth & Patrick Hanaway - Click Here